SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78f2e13ce2099069399606cfe3538eefb7d83ca7462dadc5d1a6d633dc270fe' 
  AND token = 'q67rAAkX17expeHQokZHLSQCukalONxhmjN3k8hAKOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}