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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049f74393d7c84c7be27eadef46836b8378da0c6c0ea4e7ea87f59127a20493e' 
  AND token = 'JToUZKI61YLpDKojkTnA1iObgR8kGFrzZCkuAS2Apxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}