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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66086a5a7f4fe9856087ffd3038408621920314a43fd376be412429b15db42c' 
  AND token = 'H3JuxQHykQ6IR5NSTNndDkC8OOMYYfzcC3UrnLmvOLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}