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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95ed0978d02d39982d9de79c93e818dad2d4d8a8b3a993d073927f75fa03463' 
  AND token = '+rWuV8tFuBuO/c4Y1DNqaD8oG9on+zwjyVAGSTqGaFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}