SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b1f566dcb5d9aaef3525d6f7dce9529eb454325a3f4ca07cced05e639b417e1' 
  AND token = 'PcRNrgRYOINyQyOD57rQjTUuc+Tyqs7a8L06sG2QUOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}