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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d54e522b02bb1cbff0136190c13cfa017b4dfa00712fc85ecce656c977648fd' 
  AND token = 'GfbsC25QM0PGD8KQYKPDMXkC/boR8sBNLDtcit9zPA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}