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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59355b72a1a0ea37a8d478212270a9958ad4c55d36ecb162109073a2f8213998' 
  AND token = 'zCW+kPzOfAFEbcq8kYz/3d7iYhpBMzgteTF8vNNNEAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}