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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4cdfd7527820f79b8cd18b00b2923ec9641d25d71e4de36ce9c60937273c4d' 
  AND token = 'dxriw8D8UeHkyOPkXREI26kSRAXo6zc4NtYx7r8kUGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}