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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3eae28229a0d121e01ca93746b3f1223cdc21c52d7cee1101b2016a167f734' 
  AND token = 'pnVwKtenSVZcC1KZ8o8Q7MMwP1+EIQPDoGeyeN8jYWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}