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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c378a397608ceb24539e3a03bc85b4e76062d481675c95d937f515b385d5808f' 
  AND token = 'pQr+sm5xPNGU55e+n9ZoAtXD+G+WgJH7cR2e15rfJ1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}