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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11c19fa57903f5089555eed7206b1e8995fe34239ab919724ea7b72483f8cbe4' 
  AND token = 'Cek3eqt4H3sIBDsnPUrivTofIcpKG8rL+EI50eGwJUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}