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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb79e0b1177ab33d88e066ddd5bbf77430a2f0f701153cb856d4dbccba024061' 
  AND token = 'wKp20+iM6nohD3jM7Agr6rQmKVmjRXUz12jT3ISLwjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}