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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1fb433ceec4d4b7efbacdc8f40dcb257fcb947fe8568345fbb4fa341f046c21' 
  AND token = '72PjTEPsN8q+Jz+2kyhSR9SWjVBV5GgUWbzJCTujNfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}