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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81bb44ad9e66b26423cc80f32b6cf632ba437dd8f038a73a633ac8688a44c34f' 
  AND token = 'ylo07RcD4x7n4AGfBp3I6hXTyTqF9nMP7QbRCWRsCUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}