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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f4642e2de81c931159600604c011ea72b1c23b03a9d427fca94e9ed5a192d6' 
  AND token = 'TMOdHga3ZE0TkIMFc1+onK/4wPnh148ixoccwaL9fnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}