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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4382fd89c6da190184d4ae177c3dcbd2aeeef8f29579f5f2d7ed2b16bcef9489' 
  AND token = 'd50OTTn0I5Xgwe0OhPHDd+A5fdcAWRyez9R3p9/IDhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}