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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df09336443f90dd9e5c5b6ffe8b41e4d643d524beca0a953ace4c03f437e79d3' 
  AND token = 'yUTCaVQDeFdciEiQppn/nDZ3qKQBmY+bYxvzQFD6djc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}