SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fee1d0358ddbb1afcf63585b356096bf50a91bd2ac6a27683a92734fc7478098' 
  AND token = 'd2HsOa7Cuu8TpKzkiAxdAQ2eeAG+NDucrKfDQPg9A/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}