SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9dcdc2700c949f3f7269cc35116a0959de3f760a2a7fed9d1ad1c9e502b3268' 
  AND token = 'Ru53NQqKlpm38X+JIgOuIDVr+myyrwrbR565b1SSTAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}