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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37195dd7e5886197824fe90513f19f4de1ae8b5ad320726b149c37e8d60101b9' 
  AND token = 'BDt+KH1JUBUIMc3aBx2GR1R7xyOgmojwCTzmtYxledQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}