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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ccaa84724be290aa5ad70343daa7936f7f8ed787ffe794ba604d7779c90be1' 
  AND token = 'SF6jJCJznAEZir7KlfVbkxCMNC4sVMLW8UF3I+wgtzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}