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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad22c539b25cb00f1283194fe6a5a8310a857a21f0265d52caf5f0656d6cd1df' 
  AND token = 'fFucSF3107sS4QeMDnCWBawMxYPx8lTCM6LYpT49XOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}