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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6ae6319d4ec34ec8b0151d3e6bad9e1022e4dafcfa2260497775c84c10f881' 
  AND token = '9BOmIX6xc7y+yyD1qv3RThaanoQalZQxnfkAQZkgeCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}