SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e648aa35a04f179ccf3ab60c41ffba11617aa77c82bb36ea1952657cd55f407a' 
  AND token = 'iKiJd7z+w+pQzFrOs4c/wF8PZ1fJNtqW8YVB9mtPuqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}