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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9407dc6f5c17af073431f6594d50ac5367e0c269d94997fef76d5e6ae33648c' 
  AND token = 'cpd7i8lHCsOwe/kukFKLRLv3xF1TlxPoW4eE4OxPtmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}