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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6384c042acfc6438a2c48401a565b7a77d0e39c8b7c7d88d7757f8bb34eb82' 
  AND token = 'zm9boHcyOVPkFAH8T20D0qRvtfzSn6eRq6iLgEVM1Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}