SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1761cc691c77107fc2c525f1c6c380e6b04943e8c550315aa45b131b176ff17' 
  AND token = 'r/ipKuQIZBPYMQE4Cgnu6q83vgLn35bl0ocWMBGdUxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}