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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741199747f925eede011302ea0ac2a5a0447369b49f291024a4f7be0f964fc76' 
  AND token = '2TDanxJcmc+UJmVSUd6hP0HyYU2GILnOKG6SnHzBc7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}