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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f1eb64f333c155052bfff998a055577e84d0597e89b054a5f5cef8aebd1c6e5' 
  AND token = 'hpzvPNz8ky5qWUZHE2EIXhqvVbA11PeDEkX8DKnLGyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}