SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d0ef4b7a2267fb318f6afd14757d5137c0b0c0ab1ad763a03bfa89966d5c22' 
  AND token = 'FYbHmLmvkDayd85z+UBeKmpV6w2iXEc54MOusw25oGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}