SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78399b451f8fb376ac9679ccee4f38cc3b2d09771be9d6520f73e0d240a58c87' 
  AND token = 'ZBeriduF9NDjSnl8am+j+g7/0K9qAcT7OaXdG1/h/3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}