SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2ebc1092d39da69105b3cc2a0f691554ec33dff1a7e1a19dd67d9d7a33f81b' 
  AND token = 'EVfIrOsHcT7zVo/3hVAmDx6TfOsZOieFEvDm8ZUnzcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}