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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c38ac17b1b2dfce27b43787abf792607c60646bbac05486b3032ee9da6bfc45' 
  AND token = 'CM+ltmVbcmT/8FAh+LbzR9en7czeqqUXY6Yd5CZn7JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}