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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28279d77da3e04a40e69a92b8b871cd5db3afbb9055b4f393dc6df454e1ba0a1' 
  AND token = 'ba5J10gGy0a8l8/hk4zOpE5iDd2p+r9wsIfM53FfkIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}