SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c6e0032c3624bb37de1a4c84f3b89bfac7896b39edc518126ce50733864b8b' 
  AND token = 'xTnAXOStwCRLeX+ESDP+wAIH9pQx+JcaKy5iMXmPocQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}