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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c52c04273ad8df4127e615acfe54b5bf868ee0cb2fcb9ef229480215de560f55' 
  AND token = '1k8X0DxptqbTfwPdd+Qi+2i3w6OB2vqRfB9oMpZjLSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}