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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbfb9c9a5d14b55b9029e567079b9343d37de3c607f4d1257bbaf89a8cdde599' 
  AND token = 'TZ5hnj1uJk5GxV8DF2It8llMOo9f2gpw7H56x/i/7mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}