SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0acf3a00ed41c57266b96f5883786180672786fb1e79b8b5dd5a9004af6543' 
  AND token = 'HZv1fuJX75ygcRQ9u78MG/q+IIS6IidZitU4c/y4r6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}