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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e8626148e5d384ccc5340881921c4cc5cad1249c4e1f6abc9b1b6999711fb4' 
  AND token = 'DBR28/Hf2D2NTgV9aC/GJqwtxPiqaJWEt3LRw3nN8DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}