SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fcf0ac9de4f0599639e6821b1ba07d5a5200debe12da3d732a71a8d40117e54' 
  AND token = 'P6zEAByjY14pL02b0F9uHt8XnyzoE14/ZsHcizfew0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}