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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6d5b8db9666761b32b97a41f842692e8f4c9df2320c0a8e6410a7bc0bd8c18' 
  AND token = 'B4BXwmFisCyexNBmkQDUS0QjNckxmwZiW50rUVyyKxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}