SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b615fa52c31f14c5bf34328a3096a648c863a250bc167e983ef833ce74beba' 
  AND token = 'vC1drywZ2cHDk71bSru7T33pxsY9W5aC1QKRDG5NAFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}