SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e9e24cecb50be1fb22f977eb6438a67c53a63e34b280e6c69b86ef196c0c08' 
  AND token = 'i8h288nxUDTVn5CII61LmiFGs68fOVk+s6ZsvMyxSXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}