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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeed211f9533b5ca5bb1b81fbb5acc085a8c22c8ffbe5180130ab1aec82c487d' 
  AND token = 'dp1lqyTzBVAFyB6c9HU2aF2PfvTUq+Uoa1e+LXTuzs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}