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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f035c7d2bde98124bace3db42da145fe4568bb4d13a021575b98df83dc49d2' 
  AND token = 'QpKDTI8L5HbY2JpGtWB8+vnFXbGq+D6H20OqeAZB6x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}