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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c13444441279f6c0e3eba65df92c916b7627a9e0cb4f2995a960002e3e5df1' 
  AND token = 'mkOEup70Gop4bK4QWUgtJKAdRE+2GpNhZdBflMMh9fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}