SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6846cc04e32f9e9043bfab17f53c57cdd0d460f132ffc280e2e9fee7c02bb85a' 
  AND token = 'C+5Q48Za9RMxEZVAugp/nR6S95eiVzrzQLjBQHy15bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}