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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c987dc7a565bc67aaf15154a2c982f36658a8551169446c9720da5aef294145' 
  AND token = 'Ngrv/wpndXZ1UPeHxxvgG8htA2HcbaIKRP4FJAsEA6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}