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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '614f29240cf1e34cde92a957a2517f6d89a3780803abd44510aabb68e341aba9' 
  AND token = 'iReRG2DVfcBt8OxQau6X9rDzfAz8gh+vyl75x3SQt3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}