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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce43309eaf5e5b27bcde7a7e056de291caec987fc91cadc7bbf981d8364f49a3' 
  AND token = 'Nkqytynl074+Xyv+nErQ52vYm4m9d51hkNFSxEycAwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}